Create a Harder, Larger Erection and
Last Longer in Bed with Complete Control

'Men think, while women desire.' Gone are the days when 'demanding sex' was considered exclusively a man's forte. Today's modern women demand sex greater than men. "Average" men who lack the drive, size and stamina are often not live up their women's sexual needs and appetite. It is essential to be "equipped" with the virility that is needed to give your woman the satisfaction she craves and deserves.

One herb that could help with premature ejaculation by increasing levels of serotonin is known as REVIVE 

Your penis will become engorged with blood making it harder and thicker than ever before. Your penis will swell and your veins will bulge adding additional thickness. The bulging veins will give your penis a dildo-like appearance. The additional thickness and appearance will increase her pleasure, helping to bring her to orgasm.*

TREATMENTS FOR RE-VIVE

Poor Sexual Drive (Poor Libido) - the psychic energy or instinctual drive associated with sexual desire, pleasure, or creativity. it may also refer to unwillingness to copulate on the part of a male.

Low Sperm Count (azoospermia) - absence of spermatozoa in the semen, or failure of formation of spermatozoa with resultant infertility.

Premature Ejaculation - Premature ejaculation occurs when male sexual climax (orgasm) occurs before a man wishes it or too quickly during intercourse to satisfy his partner.

There are several reasons why a man may ejaculate prematurely. For some men, the cause is due to an innate reflex or psychological predisposition of the nervous system. Sometimes it can be caused by certain drugs, such as non-prescription cold medications. Psychological factors, such as stress, fear, or guilt can also play a role. Examples of psychological factors include guilt that the sexual activity is wrong or sinful, fear of getting caught, or stress from problems at work or home.

In general, symptoms are when a male reaches climax in less than two minutes or when it occurs before the male or couple want it to occur.

Weak Sexual Organ, and all other sexual function related problems.

To stay in total control, you should take note of these:

Medical conditions; – like diabetes, prostate surgeries, etc, will affect your ability to maintain an erection. You can use our Revive along with Vigor Essential  to help make sure your erection stays Rock Hard.

Stay Erect with Revive – will alter blood flow to the nerve endings in your penis, keeping it much harder and desensitize it.

By trapping blood inside your penis – Revive will allow you to maintain an erection even after you ejaculate.*

Low Sperm Counts

Medical Examination need to be conducted first to know the sperm counts analysis level. Body cleansing is highly needed to detoxify the body system and by taking our Colon Cleansing Tea.

After 3days,our natural herb products such as Revive,V-Ca,Golden Six and Vigor Essential with be administer on the client for a specific period of time while repeat Medical Examination will unveil awesome level of sperm count,if the required level have not attained, you continue will the usage of the products.

Do you want sex to last long enough to please your partner and

feel her contractions as you bring her to multiple orgasms….

If you’re afraid your partner will laugh because you are weak in bed

Don’t allow your woman to engage in matrimonial relationship

Let her keeps your scare resources within the family instead of expending it on another ..

Stay in total control and make her ask for more…..

Here's How to Pay On Delivery

 If you are interested in this sexual enhancement and premature ejaculation killer (Revive). It will cost you just N15,000 and you will also pay for it once our courier get to your 

          address.

          and we will also give you FREE SHIPPING.  which means you will not pay for
          shipping cost.
                                                    

Sweet right?

Are you ready to lay your hand into any of this special herbal  solution?

If  you are ready to buy this penis enlargement and the premature ejaculation herbal product.

Follow The Option Below.

Option One: write down this number.+2348025305100

Then, Compose an sms in the following  format.

1 Full_Name
2 Delivery_Address
3 Phone_Number
4. The product you want to buy(REVIVE)
Send This Information to +2348025305100
 

Note. Your home or office address must be easy to locate. so that our dispatcher
        will find it easy  to locate you. If you are sending your address to us, you
        need to send  a  traceable one. Here is the sample of a traceable address.
       17A IKORODU ROAD IDIROKO Lagos State. Note. If you dont send a traceable
       address, our courier will find it difficult to locate you and hence return back
       the product to us.
       

Once we receive your order details,we will give you a call and  our partner courier company will bring the device to your address in 3 - 5 days if you are outside
       lagos or 1 to 2days if you are in Lagos.

        NOTE: If you are in lagos and you cant wait for 1 to 2 days, you can come
                     to our Marketing Company office and buy it and get your product instantly.

Thanks as we are looking forward to help you solve your bed
         harassment problem forever

For Fast, Friendly, and Secure Service Call Now

CALL  +2348025305100

“We Guarantee your Satisfaction and your Pleasure.”

Dosage Instructions:

Unlike most other herbs that must be taken for weeks or months before they even begin to work; Revive begins to work within minutes.

• For Immediate Results – take 1 to 3 capsules 1hr to 1hr:30 minutes before sex… Last much longer in bed – Finish with a more powerful orgasm – Be ready to go again in minutes.*

• Revive is Premier Tonic for Boosting Sexual Performance.

Enjoy Spontaneous Sex Anywhere, Anytime
with “Complete Control” over Your Ejaculation.*

* Everyone is different and results may vary from person to person. 

 Enhance Your Results: Take a Comprehensive Approach to Improve* Your Sexual Performance

Supplementation on its own can help with some sexual issues, but following the tips below as well will ensure peak performance between the sheets. They are also useful if you want to improve* your overall health and well-being. To be at your best:

1.      Get Plenty of Sleep (eight hours a night if possible): You already know how you feel when you skimp on your sleep. You have no energy and you’re always wishing you could sneak off for a nap. Nobody is interested in sex when they feel this way. Get more sleep for an instant libido support.

2.      Eat Well: That means eating low-fat, high-fiber foods and ones that contain complex carbohydrates. Being at your ideal weight and consuming fresh foods will both assist in improving* sexual function.

3.      Stop Stressing: Some level of stress is inevitable, but too much can literally wipe out your sex drive and result in erectile difficulties. Try stress-reducing activities and avoid unnecessary stressors in your life to improve* your mental and physical health and your sex life.

**This is a subjective assessment based on the strength of the available information and our estimation of efficacy.

*Results may vary. If you have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as medical advice. Always consult your doctor before using any supplements.

 Small Penis And Premature Ejaculation Made Me Remain Sexless For 4 Years...

But you won't believe how these simple solutions have not only helped me, but have also put smiles on my friends face.

(My true life story)

 

Before the year 2012, I had two problems, Closely related twin problems that had defiled every medication.

                                          Small Penis And Quick Ejaculation

Don't even know if you'd love hearing my boring, but heart pounding experiences in those 4 awful years...

No, I don't think so.

But the truth is that, I remained a "castrated eunuch" for 4 whole years.

It remained locked down till providence, or would I say luck smiled at me just last year July, 2015.

Funny enough; the GAME CHANGER was simple!

I never believed such a simple stunt could mean the difference in my sex life.

I'll share exactly my breakthrough with you to solve the issue of small penis and quick ejaculation.

Only promise me you're not going to finish all the babes in your area once you get access to these GAME CHANGER breakthrough.


If YES...

 Read on to continue reading my amazing story.
 

The two most shameful problems I can imagine.


Worst part is, I only realized I got the second problem  after I solved the first one,

In these whole miserable years, I only thought my problem was small penis...

I never knew it was dragging its twin brother (premature ejaculation) along.

Before I finally decided to resign to my "no sex lifestyle", two incidents happened.


Two black evil headed ugly incidents.


Ugly incident #1:

Once with a "friend", and we were in bed for the first time.

I ravaged her for hours giving her oral sex and all kinds of things.
She kept trying to touch my cock, but I would stop her.
Because I was afraid that she would be disappointed. When I finally let her touch it, I could tell that she was a bit surprised.

Even though she tried to hide it.

Later in our relationship, she finally confessed (after much prodding by me) that she was indeed shocked that my cock was so small. She was used to ones that were much larger.

She finally dumped me :(
 

Ugly incident #2:

I was fucking this babe while she lay in the prone position.

I popped out, and didn't even realize it.


I just kept going. Finally she told me that I was no longer inside her. Not only did I not realize it, but I had not been inside her for SEVERAL minutes, and had no clue.


And for your information, this has happened on more than one occasion, but this very lady finally did the unimaginable to me.

Over a slight quarrel, she went broadcasting everywhere that she's been dating a "small man"

This gave me the nickname "micro dick", and ladies  would sing that once they cite me around.


This was why I finally crossed it on everything sex, till last year.

You can't believe the simple solution that worked for me... and has worked for many.

I want to make sure you really need this solution, and that you're up to 18+

... of course, to also make sure all these big Pharmacy companies don't get hold of the information and make it exorbitantly difficult for the common man to access...

I have assumed that you're up to 18+ or more.

Great!
No time to waste... Let's go there!
I stayed 4 years without sex.

Not because I didn't have the urge, but because I never wanted another insult.
Maybe, the next insult would have led me to committing suicide.
Tufiakwa!
But then, we can't stop our love hormones from manifesting... at the right time.
In my "no sex 4 years", I immersed myself in church activities, and saw myself falling in love with one of the sisters, Adaobi.
Adaobi is a beautiful young woman, endowed with every good thing of womanhood.
Big backyard,
A set of well positioned oranges, Sexy and charming eyes Pinky lips,
Uhm... the babe is gifted.

Didn't take much time, Adaobi started visiting, and we got so close to doing it.
Of course, I'd always stop the action anytime we're getting close to doing the real do.
We would kiss for minutes, smoosh, and I'd even finger her till she squirts all over.

What was left was the penetration.
...and that's exactly what she's been dying for.
On her head, she thought;

"If this dude is this good with the other things, then he must be a champ with SEX"
But then, it wasn't just happening... until one faithful day.
We had returned from one of those boring church meetings.
While in her room, she mustered courage and asked;
"Sweerie, why don't you fuck me? Am I not good enough?"
Believe me, she barely finished saying this before broking down into tears.
Uncontrollably, I joined in the tears.

What we did next was epic... it's the reason I have a big dick today, and can last as long as I want.

Adaobi came to me, in a bid to cuddle me.

One thing led to the other, I pulled her over, and fucked her for the very first time.
Was it fun, No...
I could see the unsatisfactory expression all over her faces.
My dick wasn't enough.
This I already know...
I couldn't go as deep as my fingers could to give her that stimulation and real fucking she expected.
I broke the news...
"Baby, my johnson isn't enough"

"I'm no wood baby. I already know.

But I'm gonna help" she replied.

She told me about how her ex had the same issue, but totally and naturally reversed it with the help of a device he imported from Japan.
Long story cut short...
We imported the same device for N21,940, plus N5,000 shipping and got it after 5 days.

Did it work?
Yes, it does... 100%.
I started noticing the effect in just 2 weeks of using it.
Right now, my only regret is that we over paid for the device.
I later found another way to get the same device at 100% cheaper rate.
...and have even used the same method to get about 25 pieces of the same device for some of my readers who requested for it after reading my story.

I will tell you how to lay your hands on this powerful 2in1 secret  (plus one more bedroom must have)

Great again!

Now, before you get access to  the 24 available devices... at a 100% discounted rate,

There's one thing I absolutely think you should know.

In my opinion, you cannot do without it.

Recall that in the beginning of this article, I did mention that I suffered two problems.

Can you believe that after fixed my johnson, and increased it up to 7.3inches, I realized that...

All these while, I wasn't only suffering from small dick alone...

...But also been ravaged by the problem of premature ejaculation (PE)

Upon research online, I realized that the 2 problems go hand in hand.

Over 93% of those with the problem of small penis complained about premature ejaculation.
To that, a medical doctor friend of mine recommended to me the only no side-effect method to get rid of the problem.

Thank you loads Dr. Bola!
The solution works 100%
You start seeing results immediately. I use it and I lasted for more than 30 minutes.

The Premature Ejaculation killer work fine for me and it will do the same for you.

Combine the penis enlargement device with the premature ejaculation solution and you're ready to fire anything fireable.

Boyyyyyy.

If you are the type that can't last longer in bed, I will advice you to get this premature ejaculation killer.(REVIVE)

I use it to cure my premature ejaculation and you too can.

N15,000 ONLY Per Bottle

(Instead of N19,000 )

REVIVE is made of a pure herbal ingredients produced to boost male sexual performance. The main mechanism of REVIVE to improve sex appeal is increase reflection of nerve condition. With revive, you enjoy bigger and harder erections!



REVIVE relieves premature ejaculation effectively and other erections difficulties caused by physical or psychological factors.

You can charge your sexual life with just 2 capsules of REVIVE as a dose twice in a week or (in serious cases) especially people suffering from diabetes or on HBP drugs 4 capsules once a week. The action of REVIVE starts within 3 or 4 hours and stay active in your body.

You do not use REVIVE every time you need to have sex, with 2 capsules weekly, you will be able to gain hard lasting erection whenever you desire to have sex no matter how frequent.



REVIVE is very safe to use, even on short term basis. You gain erection when you are ready to have sex, no matter how frequent it is. You are naturally and sexually active.

Due to the efficacy of REVIVE. NAFDAC  put their trust on it and it is approved by them.

The Premature Ejaculation Killer(Revive) Will Cost You Just N15,000.

We know that you are eager to pay for this handsome up penis enlargement device and premature Ejaculation killer Revive)

But, to show you that this real and it can help you to instantly get the respect you deserve from your partner, We have arrange with  our shipping company to ship this  2in1 solution to you  without having to pay to any of our company account

Once you see the device, you can pay for it.

This is what we call Cash on Delivery.

African economists discuss impact of job-hunting doctors on healthcare quality

Poor working conditions for doctors, nurses and health technicians has a huge effect on the quality of healthcare as it pushes the health workers to hold several jobs at the same time.

This is the finding of a new research by Gaston Brice Nkoumou Ngoa, an economist at the University of Yaoundé whose research attributes the job-hopping practice to unpredictable pay for health workers. 

The research on labour income of healthcareThe research on labour income of healthcare workers and multiple job-holders in urban centres in Cameroon focused on 827 healthcare workers who blamed their moonlighting practice on low income from their first or regular job. The research found 24 per cent of the workers had second or third jobs.

However, 74 per cent of the health workers remained loyal to one job. The research on labour behaviour and response to changes in incomes focused on workers, of which 11 per cent were doctors, 54 per cent nurses and 22 per cent health technicians and laboratory attendants.

The researcher told a session “Promoting Social Inclusion in Africa” at the 10^th African Economic Conference in Kinshasa on Tuesday that the holding of multiple jobs affects the ability of the poor people to access healthcare.

“The healthcare workers behave differently in the job market. They focus on jobs which bring high income and hold several jobs because of financial motivation. This is because of the feeling of job insecurity on their main job,” Ngoa said.

According to him, some workers held a second job for reasons not linked to the need to provide healthcare but for extortion and guaranteed access to illicit forms of money-making and graft.

Ngoa attributed the explosion of the second jobs to salary cuts targeting civil servants and the depreciation of currencies in the 1990s, which affected household incomes.

His paper advocated for an end to the practice because it distorted the labour and employment market and affected service delivery.

“The impact of this practice is significant. Those with a second job are also those with low income jobs, mostly nurses and their working conditions are worsening. Policy should focus on discouraging this practice by giving bonuses to those willing to stick to one job.”

The AEC, jointly organized by the African Development Bank AfDB, the UN Economic Commission for Africa and the UN Development Programme, is focusing its attention on fighting poverty. Its poverty fighting agenda is based on new ways of ensuring economic growth result into benefits.

The three-day conference ends Wednesday.

Describing the labour market research as a new development on economic science, UNDP official Isiyaka Sabo said the evidence showed peculiar working hours mostly encouraged health workers to look for a second job. This means the incomes from those jobs remained low.

Poor working conditions for doctors, nurses and health technicians has a huge effect on the quality of healthcare as it pushes the health workers to hold several jobs at the same time.

This is the finding of a new research by Gaston Brice Nkoumou Ngoa, an economist at the University of Yaoundé whose research attributes the job-hopping practice to unpredictable pay for health workers. 

The research on labour income of healthcareThe research on labour income of healthcare workers and multiple job-holders in urban centres in Cameroon focused on 827 healthcare workers who blamed their moonlighting practice on low income from their first or regular job. The research found 24 per cent of the workers had second or third jobs.

However, 74 per cent of the health workers remained loyal to one job. The research on labour behaviour and response to changes in incomes focused on workers, of which 11 per cent were doctors, 54 per cent nurses and 22 per cent health technicians and laboratory attendants.

The researcher told a session “Promoting Social Inclusion in Africa” at the 10^th African Economic Conference in Kinshasa on Tuesday that the holding of multiple jobs affects the ability of the poor people to access healthcare.

“The healthcare workers behave differently in the job market. They focus on jobs which bring high income and hold several jobs because of financial motivation. This is because of the feeling of job insecurity on their main job,” Ngoa said.

According to him, some workers held a second job for reasons not linked to the need to provide healthcare but for extortion and guaranteed access to illicit forms of money-making and graft.

Ngoa attributed the explosion of the second jobs to salary cuts targeting civil servants and the depreciation of currencies in the 1990s, which affected household incomes.

His paper advocated for an end to the practice because it distorted the labour and employment market and affected service delivery.

“The impact of this practice is significant. Those with a second job are also those with low income jobs, mostly nurses and their working conditions are worsening. Policy should focus on discouraging this practice by giving bonuses to those willing to stick to one job.”

The AEC, jointly organized by the African Development Bank AfDB, the UN Economic Commission for Africa and the UN Development Programme, is focusing its attention on fighting poverty. Its poverty fighting agenda is based on new ways of ensuring economic growth result into benefits.

The three-day conference ends Wednesday.

Describing the labour market research as a new development on economic science, UNDP official Isiyaka Sabo said the evidence showed peculiar working hours mostly encouraged health workers to look for a second job. This means the incomes from those jobs remained low.

Breast cancer

Women who go on to develop breast cancer tend to have breasts that are less symmetrical than women who don't develop the cancer. A study published in Breast Cancer Research reveals that breast asymmetry could be a reliable independent predictor of breast cancer.

The study found that the relative odds of developing breast cancer increased by 1.5 with each 100ml increase in breast asymmetry.

Diane Scutt from the University of Liverpool, UK and colleagues studied the mammograms of 252 women who did not have breast cancer at the time of the mammography, but later on developed the disease. The control group consisted of 252 women matched for age who underwent mammography at the same time, but did not develop breast cancer.

Scutt et al.'s results show that, at the time the mammography was done, women who went on to develop breast cancer had higher breast volume asymmetry than controls. The authors found that the relative odds of breast cancer increased by 1.5 for a 100ml increase in absolute breast volume asymmetry, after adjusting for other potential risk factors. They conclude that breast asymmetry is a significant independent predictor of breast cancer, and could be a reliable indicator of future breast disease.

Article: Breast asymmetry and predisposition to breast cancer.  Diane Scutt and John T Manning. Breast Cancer Research 2006, 8:R14 (20 March 2006)

---

Story Source:

The above post is reprinted from materials provided by BioMed Central.Note: Materials may be edited for content and length.

Researchers identify potential new leukemia drug target

New treatment options are badly needed for acute myeloid leukemia, a relatively rare form of cancer. The malignancy begins in the bone marrow, and from there can spread rapidly to the bloodstream, depriving the body of the essential blood cells that carry oxygen and fight infections.

The image shows cancerous mouse bone marrow cells generated by the mutant protein AE, found in 15 percent of acute myeloid leukemia patients. Using AE as an entry point, the researchers found another protein that prompts similar changes in gene activation.

Now, new work from a team lead by Rockefeller University researchers has revealed a potential genetic weakness of the disease, offering insights into the molecular mechanisms behind acute myeloid leukemia and suggesting a new target for drug development.

Previously, researchers identified a variety of mutations associated with this disease, including a DNA rearrangement found in about 15 percent of patients. The abnormal DNA-binding protein produced as a result of this mutation takes on entirely new functions, dramatically altering a set of genes that are turned on in a cell to promote the cancer. But how this mutation affects these changes has remained mysterious.

In their new work published on October 21 in Genes and Development, the researchers describe how they identified the molecular mechanism behind this gene activation.

The researchers, led by Robert G. Roeder, Arnold and Mabel Beckman Professor and head of Rockefeller's Laboratory of Biochemistry and Molecular Biology, began by searching for proteins that interact with the mutant protein, known as AE, produced by a DNA rearrangement. Their screen identified JMJD1C, an enzyme that removes chemical tags, known as methyl groups, from histones, which are proteins contained in chromosomes. These tags serve as repressive marks, indicating that genes in the associated region should be turned off.

To investigate the relationship between JMJD1C and AE, the team first explored the broader effects of removing JMJD1C. "We found that numerous genes were down-regulated upon loss of JMJD1C, and the set overlaps significantly with the genes that are normally activated by AE," explains first author Mo Chen, a postdoc in Roeder's lab.

The loss of gene expression turns out to have dramatic consequences for the disease. The team found that acute myeloid leukemia cells are addicted to the presence of JMJD1C, and without it they cannot survive. "In fact, these cells were very sensitive to depletion of JMJD1C," says Chen. "We see an increase in apoptosis, a sort of cellular suicide."

The team confirmed that JMJD1C interacts with AE, and demonstrated that the enzyme is required for AE to exert its cancer-promoting effects. But they also found that JMJD1C plays an even a broader role in acute myeloid leukemia, beyond its interaction with AE.

"We were very surprised to find that JMJD1C is required for the proliferation of other acute myeloid leukemia cell lines, which do not have AE, so we looked for other proteins that might be responsible for JMJD1C addiction," says Chen. The team found at least two other proteins that can recruit JMJD1C to target genes in diseased cells that lack AE, fueling leukemia growth.

These results suggest that JMJD1C may play a general role in promoting growth in myeloid leukemias, according to the researchers. "We are excited because this type of general phenomena is an ideal target for drug development," Roeder says.

There are already small molecules that inhibit this class of enzymes. "Our work will facilitate the development of selectiive inhibitors against JMJD1C, which is a highly promising therapeutic target for multiple types of leukemia," Roeder adds.

Coffee may help perk up your blood vessels

The caffeine in a cup of coffee might help your small blood vessels work better, according to research presented at the American Heart Association's Scientific Sessions 2013.

The caffeine in a cup of coffee might help your small blood vessels work better.

A study of 27 healthy adults showed -- for the first time -- that drinking a cup of caffeinated coffee significantly improved blood flow in a finger, which is a measure of how well the inner lining of the body's smaller blood vessels work. Specifically, participants who drank a cup of caffeinated coffee had a 30 percent increase in blood flow over a 75-minute period compared to those who drank decaffeinated coffee.

"This gives us a clue about how coffee may help improve cardiovascular health," said Masato Tsutsui, M.D., Ph.D., lead researcher and a cardiologist and professor in the pharmacology department at the University of the Ryukyus in Okinawa, Japan.

The study adds to a growing body of research about coffee, the most widely consumed beverage worldwide. Previous studies showed that drinking coffee is linked to lower risks of dying from heart disease and stroke, and that high doses of caffeine may improve the function of larger arteries.

Study participants were people who did not regularly drink coffee, ranging in age from 22 to 30. On one day, each participant drank one five-ounce cup of either regular or decaffeinated coffee. Then researchers measured finger blood flow with laser Doppler flowmetry, a non-invasive technique for gauging blood circulation on a microscopic level. Two days later, the experiment was repeated with the other type of coffee. Neither the researchers nor the participants knew when they were drinking caffeinated coffee.

The researchers noted blood pressure, heart rate, and vascular resistance levels. They also took blood samples to analyze levels of caffeine and to rule out the role of hormones on blood vessel function.

Compared to decaf, caffeinated coffee slightly raised participants' blood pressure and improved vessel inner lining function. Heart rate levels were the same between the two groups.

It's still unclear how caffeine actually works to improve small blood vessel function, although Tsutsui suggests that caffeine may help open blood vessels and reduce inflammation.

"If we know how the positive effects of coffee work, it could lead to a new treatment strategy for cardiovascular disease in the future," said Tsutsui.

---

Story Source:

The above post is reprinted from materials provided by American Heart Association. Note: Materials may be edited for content and length.

Drinking coffee daily may improve survival in colon cancer patients

Regular consumption of caffeinated coffee may help prevent the return of colon cancer after treatment and improve the chances of a cure, according to a new, large study from Dana-Farber Cancer Institute that reported this striking association for the first time.

Colon cancer patients, all of them treated with surgery and chemotherapy for stage III colon cancer, had the greatest benefit from consuming four or more cups of coffee a day.

The patients, all of them treated with surgery and chemotherapy for stage III colon cancer, had the greatest benefit from consuming four or more cups of coffee a day (about 460 milligrams of caffeine), according to the study published in the Journal of Clinical Oncology. These patients were 42 percent less likely to have their cancer return than non-coffee drinkers, and were 33 percent less likely to die from cancer or any other cause.

Two to three cups of coffee daily had a more modest benefit, while little protection was associated with one cup or less, reported the researchers, led by Charles Fuchs, MD, MPH, director of the Gastrointestinal Cancer Center at Dana-Farber. First author is Brendan J. Guercio, MD, also of Dana-Farber.

The study included nearly 1,000 patients who filled out dietary pattern questionnaires early in the study, during chemotherapy and again about a year later. This "prospective" design eliminated patients' need to recall their coffee-drinking habits years later -- a source of potential bias in many observational studies.

"We found that coffee drinkers had a lower risk of the cancer coming back and a significantly greater survival and chance of a cure," Fuchs said. Most recurrences happen within five years of treatment and are uncommon after that, he noted. In patients with stage III disease, the cancer has been found in the lymph nodes near the original tumor but there are no signs of further metastasis. Fuchs said these patients have about a 35 percent chance of recurrence.

As encouraging as the results appear to be, Fuchs is hesitant to make recommendations to patients until the results are confirmed in other studies. "If you are a coffee drinker and are being treated for colon cancer, don't stop," he said. "But if you're not a coffee drinker and wondering whether to start, you should first discuss it with your physician."

Fuchs said the study is the first to study an association between caffeinated coffee and risk of colon cancer recurrence. It adds to a number of recent studies suggesting that coffee may have protective effects against the development of several kinds of cancer, including reduced risks of postmenopausal breast cancer, melanoma, liver cancer, advanced prostate cancer.

Fuchs said the research focused on coffee and other dietary factors because coffee drinking -- in addition to possibly being protective against some cancers -- had been shown to reduce the risk of type 2 diabetes. Risk factors for diabetes -- obesity, a sedentary life style, a Western diet high in calories and sugar, and high levels of insulin -- are also implicated in colon cancer.

In analyzing the results of the new study, Fuchs and his colleagues discovered that the lowered risk of cancer recurrence and deaths was entirely due to caffeine and not other components of coffee. He said it's not clear why caffeine has this effect and the question needs further study. One hypothesis is that caffeine consumption increases the body's sensitivity to insulin so less of it is needed, which in turn may help reduce inflammation -- a risk factor for diabetes and cancer, Fuchs said.

Other than drinking coffee, Fuchs said, people can take other measures to reduce cancer risks -- avoiding obesity, exercising regularly, adopting a healthier diet, and eating nuts, which also reduce the risk of diabetes.

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Story Source:

The above post is reprinted from materials provided by Dana-Farber Cancer Institute. Note: Materials may be edited for content and length.